想生BB 今日: 2 | 主題: 109087

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發表於 11-3-8 18:01 |只看該作者

Hello Myb,

Yes, I work in an IVF lab.

You do have a number of questions; I will try to answer them one by one here:

1. Using donor eggs will be one of the better options. Finding an appropriate donor, ethical concerns, and financial support are other considerations you may need to think about.

2. You should not view IVF as an endless journey. IVF helps to increase the chance of having a baby, but it does not guarantee it. There are certainly couples who have gone through IVF but remain childless.

3. All fertility specialists are properly trained and licensed to treat; I can't recommend one or a few particular names. However, you may want to seek opinions from a few and see if they would offer further treatment or other options.

4. 有錢不等如一切; 做十次八次,總有一次得 is not a good spirit. You need to understand your short-coming, set a goal or timeline for yourself, know when to stop or hopefully go with another plan.

cutecutetown

原帖由 Myb 於 11-3-7 22:21 發表
Cutecutetown你好,

你對生育及IVF的知識真豐富呢, 有事請教你呢.
你是不是在生育診所做的呢..

我情況其實一點也不樂觀,因為我兩側卵巢因朱古力瘤都做過手術,M後照超聲都係3-4粒,只有一側有反應,另一則因手術割得過 ...

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683^#

發表於 11-3-8 18:16 |只看該作者

Hello susumi123,

I think it can be both, mostly the embryo quality but perhaps the 子宮肌留also affect implantation.

This is only your 1st-time IVF. The sensible thing to do is to do your coming FET. If it fails again, try to get a second opinion of your 子宮肌留 to see if it needs to be removed. Then a 2nd IVF may give a better outcome. No guarantee here, but based on the no. of eggs you have and the presence of sperm in TESE, it is worthwhile to try again.

cutecutetown

原帖由 susumi123 於 11-3-8 07:14 發表
Hi cutecutetown,

This is my first time posting a question here, hope you can give me some opinion.

My hubby did SA last year and found zero sperm in his sample, that means NO sperm at all. and he we ...

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superwife

大宅

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684^#

發表於 11-3-8 21:53 |只看該作者

Dear Cutecutetown,

I agree with you that my ivf doctor is over-cautious. I am taking the Cyclogest 400mg twice daily and 100mg progesterone once daily up to 12 weeks, which I think is too too much...

The doctor said that since the hcg is going high, yesterday (day 21 after ER or 5 weeks) was 9800, which was fast double 2 days ago, he still assumes that twins probably might happen to me. He is still worry about the one which can be seen at the moment. There still possibility of having 1 in the uterus and 1 is ectopic.... So another scan will be made on Friday. We are still worry...

Actually when will be the lastest time to discover a ectopic?

What is the usual hcg in week 4 and 5? Am I really "too high". Will it hurt if it's "too high" to one embryo?

Still worry.....
Thanks for giving me a way to release....
I will keep you post. Hopefullly good news are coming very soon...

原帖由 cutecutetown 於 11-3-7 16:14 發表
Dear superwife,

I am glad for you but a little upset by your ivf doctor. I don't know how many ivf docs out there who would ask their patients to do an ultrasound scan in

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685^#

發表於 11-3-8 23:25 |只看該作者

Dear sukudo,

That's good to know. Quite a good start after all the months of waiting, and when most follicles look ripe (~18mm or more), I am guessing you will probably get your 破卵針 on Thur. or Fri.

E2 is produced by growing follicles. It gives us a reference point to compare with the follicle size as appeared on the ultrasound. Besides, when it rises sky-high (>20,000), doctors will take precautionary steps to avoid OHSS. In your case when E2 is 4000-5000, you really don't have to worry about 過渡刺激卵巢 at all. E2 levels measured at different time before and during the stimulation process have to be interpreted with other clinical findings to be meaningful.

To drink water before ET is to fill up your urinary bladder. A full bladder somewhat presses on the uterus so that the path for ET is straighter. In other words, with ultrasound guidance, the ET process will be more straight forward and the embryos can be placed inside the uterus with much ease. It helps you in the sense that you will experience less pain during ET. As long as the embryos can be placed into the uterus, the full bladder doesn't directly help (nor harm) implantation.

cutecutetown

原帖由 sukudo 於 11-3-8 16:21 發表
cutecutetown

係我呀, 我今次E2合格啦, DAY 3時 E2係149, 終於開始左IVF, 不過我對針藥既反應比較慢, 我今日已經打左13日針, 除左頭2日打450, 其他日日都打300, 沈日照到有5-6粒, 每粒都係13-14mm, 而E2係4千幾, 我 ...

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686^#

發表於 11-3-8 23:53 |只看該作者

Dear superwife,

Thanks for telling me your progress. I still think the chance of an ectopic is relatively small, although we will need to confirm with a scan on Friday.

As soon as a prominent sac or even a beating fetal heart can be clearly seen on the ultrasound, anything ectopic should show up as well (being similar size or slightly smaller to the one inside the uterus).

Depending on the number of fetuses inside, hcg level varies, and there really is no "should be" hcg. In ivf pregnancies, hcg is almost always much higher than those of natural pregnancies during early gestation. This may also be one of the reasons why some general gynaecologists couldn't relate the high values with small/none gestational sac because the chemistry is different. I don't have the expertise to comment; however, I wonder if your doctor should at least reduce your Cyclogest/progesterone a little.

hcg is produced by the implanted embryo, so in theory, a high level is just a sign that the embryo is growing and shouldn't be harmful. Up to a certain level (usually by 8-10 weeks), the level will pleateau and become stable.

Cheers,
cutecutetown

原帖由 superwife 於 11-3-8 21:53 發表
Dear Cutecutetown,

I agree with you that my ivf doctor is over-cautious. I am taking the Cyclogest 400mg twice daily and 100mg progesterone once daily up to 12 weeks, which I think is too too much... ...

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blythe_kiss

大宅

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發表於 11-3-9 06:10 |只看該作者

cutecutetown, many thanks for your advice. :D

原帖由 cutecutetown 於 11-3-6 23:08 發表
Hi blythe_kiss,

No worry la, your FSH is fine; day1 and day2 should be similar, although there may also be a slight cycle-to-cycle variation.

Whether your FSH is high or low is only one of the facto ...

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parker123

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688^#

發表於 11-3-9 09:37 |只看該作者

Cutecutetown,

Thank you for your reply. I have talked to my hubby but it looks like we both are not sure what to do next. In fact, I don't think I can be perfectly OK for IVF emotionally and will not be since there are so many ups and downs during the procedure. However, I have done it twice and with the gained experience, I am much better than before. Initially, I'm thinking if my FSH is below 8 in the next cycle, I will give another try otherwise will wait for next. Let the statistics to decide my next move. Do you think it is a sensible approach? Is FSH 8 a good benchmark? Any other benchmark I need to use?

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susumi123

珍珠宮

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689^#

發表於 11-3-9 12:06 |只看該作者

Hi cutecutetown,

Thank you for your reply and thank you so much for you to spend so much time for answering our question.

I have one more question, is my embryos grading very poor? (G2+, G2, G2-) There's no G1, is that only G1 embryo can be successful? Did you see any case with G2- success?

Also, as per my doctor, the sperm quality seems affecting my embryos quailty. We've got 5 tubes of sperm last time, and they used 2 tubes for my 1st IVF. However, all my embryos are coming out from the same TESE sperm, even if I try another IVF, would the sperm quality the same as this time, or is there any difference between each tube?

原帖由 cutecutetown 於 11-3-8 18:16 發表
Hello susumi123,

I think it can be both, mostly the embryo quality but perhaps the 子宮肌留also affect implantation.

This is only your 1st-time IVF. The sensible thing to do is to do your coming FE ...

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690^#

發表於 11-3-9 13:41 |只看該作者

Dear parker123,

That's sensible enough. The FSH level you set is a measureable benchmark; other than this, your doc will probably do an ultrasound scan as well. See what he/she thinks. Also, take your emotional state on that day into the equation. When you are truly ready to start the "journey", then I am always on your side too.

I know you seem to have only one functional ovary and most docs will "push" it hard to get eggs. See if you can get a milder stimulation to get a cohort with good quality (instead of quantity). This really depends on your doc though, I am only suggesting.

Cheers, cutecutetown

原帖由 parker123 於 11-3-9 09:37 發表
Cutecutetown,

Thank you for your reply. I have talked to my hubby but it looks like we both are not sure what to do next. In fact, I don't think I can be perfectly OK for IVF emotionally and will n ...

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發表於 11-3-9 14:12 |只看該作者

Dear susumi123,

Embryo grading is indeed a very subjective assessment on the embryo appearance only. Just like buying oranges in a supermarket, we will all choose to buy the good-looking ones. But that is in relative terms; suppose you go to the market in the evening instead of in the morning, you should still find good oranges even though many believe that produces may be fresher in the morning. Whether you have picked and bought a good one or an average one, they are probably equally good and sweet inside. The only thing for certain is that you don't buy an orange that appear rotten on the outside.

Similar logic to us looking at embryos, no doubt that the "rotten" ones would have been excluded from the usable pool. When we think the embryos have potential, we would either transfer or freeze for later use. So again, when we have to compare these usable embryos to each other, we have this natural tendency to think that the average-looking ones may not be as nice as the good-looking ones. However, I don't see all G1 embryos implant, and I don't see all G2/G2- embryos fail either.

The sperm quality should probably be the same and there is no difference in between tubes. Based on your embryo quality, I still think your egg quality (which led to embryo quality later) is no.1 concern, then no.2 is the 子宮肌留, sperm comes much lower in the list. This is based on what you told me in your last message, without knowing your age and other infertility cause(s).

cutecutetown

原帖由 susumi123 於 11-3-9 12:06 發表
Hi cutecutetown,

Thank you for your reply and thank you so much for you to spend so much time for answering our question.

I have one more question, is my embryos grading very poor? (G2+, G2, G2-) Th ...

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sukudo

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692^#

發表於 11-3-9 14:19 |只看該作者

原帖由 cutecutetown 於 11-3-8 23:25 發表
Dear sukudo,

That's good to know. Quite a good start after all the months of waiting, and when most follicles look ripe (~18mm or more), I am guessing you will probably get your 破卵針 on Thur. or F ...

cutecutetown
我今晚打破卵針啦, 5粒around 18-20mm, 星期5抽蛋, 一向醫生都request病人隔1日放胎, 不過我今次隔左2日, 我下星期一先放胎, 唔知有咩分別呢?

另外, 好想問, 你地係唔係建議太太放胎後第2日照常返工架? 其實休息都幫助不大?

我好開心行到呢1步, 我好多謝你呀, 你一直都好支持我, 而今日我終於行到了....

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693^#

發表於 11-3-9 22:42 |只看該作者

Dear sukudo,

Good progress! I am very excited for you.

There is in fact no dramatic difference between a day-2 and a day-3 ET. I personally prefer a day-3 (i.e. what you will have) because one more day of growth in the lab usually allows better selection. In cases where embryos are just so-so, day-3 definitely let us select the nicer embryos for ET. In cases where all embryos are good-looking, then it doesn't really matter which day.

In theory, you can resume your daily activities (work, shop, rest, etc.) on the day of ET. I think the key is to relax and not to feel over-stressed. The 2 weeks of waiting for a bingo test are really some harsh time to "kill". If work can distract you from thinking too much, go back to work. If you feel like resting for a few days, it should be fine as well. I can feel you are quite an optimistic person, so, go with what you feel like.

Now, after this successful first step, there is still some distance ahead to walk through. Feel free to express yourself here :)
cutecutetown

原帖由 sukudo 於 11-3-9 14:19 發表

cutecutetown
我今晚打破卵針啦, 5粒around 18-20mm, 星期5抽蛋, 一向醫生都request病人隔1日放胎, 不過我今次隔左2日, 我下星期一先放胎, 唔知有咩分別呢?

另外, 好想問, 你地係唔係建議太太放胎後第2日照常返工 ...

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積分: 306

694^#

發表於 11-3-9 23:14 |只看該作者

相信您日常的工作要求很精確，必定很累吧，但您仍在工餘時間，以專業知識，解答了我們心中的疑慮，實作很感謝。
我明天《放榜》了，希望有好消息給您…如有的話，我想我只會給你一個哈哈笑，便代表了第一步成功。

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695^#

發表於 11-3-10 13:40 |只看該作者

I am failed.
But I will not give up.
Thank you.

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696^#

發表於 11-3-10 21:18 |只看該作者

Dear Creamother,

Uh???? That's really strange and you got me worried. No pressure though, tell me only when you are ready and up to it.

cutecutetown

原帖由 Creamother 於 11-3-10 13:40 發表
I am failed.
But I will not give up.
Thank you.

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697^#

發表於 11-3-10 22:12 |只看該作者

My period has not yet come. My blood test result this morning is less than one, indocating not pregnancy. I miscarriage once. I tried for four years and i preg natrually on 2006. My son is four yrs old now. I love him so much. But during my 26week , I am told I am diabetics. The doctor said might be cured after giving birth.but I am still a diabetic. 也許我十一歲甲狀腺有問題，至十九歲做手術後痊癒，現時亦有定期驗。but no supplement is needed. I reduced my weight fr 65kg to50kg in six months and I had my son natrually while I was waiting ivf in WH.
My husband'sperm is not so good, low mobility, normal one is only 5%.
I had a son. He wants playmate soooooo much. 我告訴他，找了很久，也找不到bb，他說：媽咪，比心機搵啦，比心機就得啦，還拍拍我膊頭。
quote]原帖由 cutecutetown 於 11-3-10 21:18 發表

Dear Creamother,

Uh???? That's really strange and you got me worried. No pressure though, tell me only when you are ready and up to it.

cutecutetown

[/quote]

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